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checkcif_Cleogynone A.pdf (120.52 kB)
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cleogynone A elemental comp.tif (76.71 kB)
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Cleogynone A FTIR.tif (213.68 kB)
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Cleogynone A HMBC.jpeg (284.38 kB)
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Cleogynone A HNMR.jpeg (319.44 kB)
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Cleogynone A HSQC.jpeg (254.27 kB)
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Cleogynone A Noesy.jpeg (416.48 kB)
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Cleogynone A1 Cnmr.jpeg (397.26 kB)
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Cleogynone A1 DEPTnmr.jpeg (320.14 kB)
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FTIR cleogynone A.tif (105.46 kB)
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checkcif_Cleogynone B.pdf (145.16 kB)
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Cleogynone B Ftir.tif (210.68 kB)
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Bioactive ingredients from Cleome gynandra and their encapsulation in beta-cyclodextrin

dataset
posted on 2022-07-07, 12:35 authored by Buntubonke GomBuntubonke Gom, Vinesh J. Maharaj, Philip Labuschagne, Nomusa R. Dlamini

These datasets were used for my PhD Thesis titled 'Identification of bioactive ingredients from Cleome gynandra and the physicochemical study of their microencapsulation in beta-cyclodextrin'.The same datasets also form part of a journal contribution titled 'Dammarane-type triterpenoids with anti-cancer activity from the leaves of Cleome gynandra' published in Phytochemistry Letters vol.43, 2021, pp.16-22. 

The dataset includes information on novel compound structure elucidation datasets (1D and 2D NMR, single-crystal X-ray diffraction, FTIR and elemental composition), alpha glucosidase inhibition assays (extracts and semi-pure fractions), cancer cytotoxicity (lung-, breast- and colorectal cancer).

Funding

Department of Science and Innovation

Council for Scientific and Industrial Research

History

Department/Unit

Chemistry