University of Pretoria
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Follicle-Stimulating Hormone receptor Antagonist effect on osteoclast maturation and formation

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posted on 2025-07-01, 08:25 authored by Jacobus ScheepersJacobus Scheepers
<p dir="ltr">The data set contain information regarding cell viability testing, concentration testing and osteoclast formation. Information was collected using various <i>in vitro </i>techniques including western blotting, resazurin viability testing and tartrate resistant acid phosphatase staining and activity. RAW 264.7 murine macrophages were used as a base which was modified to express wild-type human follicle-stimulating hormone receptor (FSHR). The data set was analyzed using GraphPad Prism 7 and ImageJ. The statistical analysis employed one-way ANOVA and to avoid false positives the Bonferroni correction was utilized in multiple comparisons. No significant conclusions were drawn from the study due to further investigation being required.</p>

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