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Sequencing data and statistical analysis for evaluation of evolution within HIV-1 polymerase gene
journal contribution
posted on 2022-09-12, 14:17 authored by Paballo NkonePaballo Nkone, Simnikiwe H. Mayaphi, Caroline T Tiemessen, Shayne Loubser, Thomas C. Quinn, Andrew D. ReddThis is data that was analysed for my dissertation titled 'Molecular characterisation and assessment of evolution of the HIV-1 polymerase gene during early and chronic HIV-1 infection'. The same data was used for a journal article titled 'Deep sequencing of the HIV-1 polymerase gene for characterisation of cytotoxic T-lymphocyte epitopes during early and chronic disease stages' published on Virology Journal volume 19, Article number: 56 (2022)
The dataset included data on prediction of HIV-1 pol CTL epitopes and data on using sequence diversity and Shannon entropy for identifying recent infections.