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Storage stability of NP.xlsx (13.09 kB)
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Initial DLS of Nanoformulations.xlsx (11.62 kB)
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Stability over time DLS of each NP.xlsx (24.32 kB)
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DLC (%) and EE (%) of Nanoparticles.xlsx (31.92 kB)
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Cytotox calculations.xlsx (194.22 kB)
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Characterizations of the poly-(lactide-co-glycolide) (PLGA) nanoparticles and cytotoxic analysis

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posted on 2023-11-14, 13:13 authored by Bianca DiedericksBianca Diedericks

The data includes Excel sheets of Dynamic Light Scattering (DLS) of the initial size, polydispersity index (PdI) and Zeta potential of the nanoparticles. Dynamic Light Scattering (DLS) of the stability in storage conditions which included size, polydispersity index (PdI), Zeta potential and pH of the nanoparticles over 6 Months.

Dynamic Light Scattering (DLS) of the nanoparticles in different media over 7 days.

  • Calculations of the drug loading capacity (%) and the encapsulation efficiency (%) of 7-Methyljuglone (7-MJ) and Rhodamine B (RhB) into the poly-(lactide-co-glycolide) (PLGA) nanoparticles

    • The characterization of the Blank nanoparticles, 7-Methyljuglone (7-MJ) nanoparticles, and 7-Methyljuglone + Rhodamine B (7-MJ+RhB) nanoparticles.

    The cytotoxic effect of 7-Methyljuglone (7-MJ) and the Blank nanoparticles, 7-Methyljuglone (7-MJ) nanoparticles and 7-Methyljuglone + Rhodamine B (7-MJ+RhB) nanoparticles are also attached, this excel sheet includes the plate layout, calculations and data generated using GraphPad Prism to maintain the half-maximal inhibitory concentration (IC50) of these compounds.

    Funding

    National Research Foundation (NRF), Grant Number: 98334

    History

    Department/Unit

    Plant and Soil Science

    Sustainable Development Goals

    • 3 Good Health and Well-Being
    • 9 Industry, Innovation and Infrastructure
    • 12 Responsible Consumption and Production

    Usage metrics

      Natural and Agricultural Sciences

      Categories

      Keywords

      Mycobacterium tuberculoisCytotoxicity 20Characterization analysis resultsNanoparticle characteristicsNanoparticle agglomerate sizePoly-(lactide-co-glycolide) (PLGA)Poly-(lactide-co-glycolide) PLGA) nanostructuresSDG 3 Good health and wellbeingSDG 9 Industry, innovation and infrastructure

      Licence

      CC BY 4.0

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