Characterizations of the poly-(lactide-co-glycolide) (PLGA) nanoparticles and cytotoxic analysis

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posted on 2023-11-14, 13:13 authored by Bianca DiedericksBianca Diedericks

The data includes Excel sheets of Dynamic Light Scattering (DLS) of the initial size, polydispersity index (PdI) and Zeta potential of the nanoparticles. Dynamic Light Scattering (DLS) of the stability in storage conditions which included size, polydispersity index (PdI), Zeta potential and pH of the nanoparticles over 6 Months.

Dynamic Light Scattering (DLS) of the nanoparticles in different media over 7 days.

Calculations of the drug loading capacity (%) and the encapsulation efficiency (%) of 7-Methyljuglone (7-MJ) and Rhodamine B (RhB) into the poly-(lactide-co-glycolide) (PLGA) nanoparticles

The characterization of the Blank nanoparticles, 7-Methyljuglone (7-MJ) nanoparticles, and 7-Methyljuglone + Rhodamine B (7-MJ+RhB) nanoparticles.

The cytotoxic effect of 7-Methyljuglone (7-MJ) and the Blank nanoparticles, 7-Methyljuglone (7-MJ) nanoparticles and 7-Methyljuglone + Rhodamine B (7-MJ+RhB) nanoparticles are also attached, this excel sheet includes the plate layout, calculations and data generated using GraphPad Prism to maintain the half-maximal inhibitory concentration (IC₅₀) of these compounds.

Funding

National Research Foundation (NRF), Grant Number: 98334

History

Department/Unit

Plant and Soil Science

Sustainable Development Goals

3 Good Health and Well-Being
9 Industry, Innovation and Infrastructure
12 Responsible Consumption and Production

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Keywords

Mycobacterium tuberculois Cytotoxicity 20 Characterization analysis results Nanoparticle characteristics Nanoparticle agglomerate size Poly-(lactide-co-glycolide) (PLGA)Poly-(lactide-co-glycolide) PLGA) nanostructures SDG 3 Good health and wellbeing SDG 9 Industry, innovation and infrastructure

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CC BY 4.0

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