University of Pretoria
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Chrisna Durandt

Senior Scientist (Biological sciences; Biochemistry and cell biology; Health sciences)

Pretoria, South Africa

Publications

  • Effects of tetramethylpiperidine (TMP)-substituted phenazines on membrane stability and P-glycoprotein function.
  • Evaluation of the antineoplastic activities of the riminophenazine agents clofazimine and b669 in tumor-bearing rats and mice.
  • Immunosuppressive Signaling Pathways as Targeted Cancer Therapies
  • Novel riminophenazine compounds with improved anti-tumour properties
  • Evaluation of the antineoplastic activities of the riminophenazine agents clofazimine and B669 in tumor-bearing rats and mice
  • Novel fl ow cytometric approach for the detection of adipocyte subpopulations during adipogenesis
  • Pneumolysin activates neutrophil extracellular trap formation
  • Pneumolysin mediates heterotypic aggregation of neutrophils and platelets in vitro
  • Pneumolysin Mediates Platelet Activation In Vitro
  • Comparison of human platelet lysate alternatives using expired and freshly isolated platelet concentrates for adipose-derived stromal cell expansion
  • Genome-wide analysis of gene expression during adipogenesis in human adipose-derived stromal cells reveals novel patterns of gene expression during adipocyte differentiation
  • Validation of merocyanine 540 staining as a technique for assessing capacitation-related membrane destabilization of fresh dog sperm
  • Neutrophil extracellular traps and their role in health and disease
  • Clofazimine, but not isoniazid or rifampicin, augments platelet activation in vitro
  • The beta-2-adrenoreceptor agonists, formoterol and indacaterol, but not salbutamol, effectively suppress the reactivity of human neutrophils in vitro
  • Targeting the aryl hydrocarbon receptor nuclear translocator complex with DMOG and Stemregenin 1 improves primitive hematopoietic stem cell expansion
  • Human adipose derived mesenchymal stromal cells transduced with GFP lentiviral vectors: assessment of immunophenotype and differentiation capacity in vitro
  • Sperm macrocephaly syndrome in the ostrich Struthio camelus: Morphological characteristics and implications for motility
  • The Effect of Early Rounds of ex vivo Expansion and Cryopreservation on the Adipogenic Differentiation Capacity of Adipose-Derived Stromal/Stem Cells
  • Introduction of the AmpliChip CYP450 Test to a South African cohort: a platform comparative prospective cohort study.
  • Pneumolysin activates the synthesis and release of interleukin-8 by human neutrophils in vitro.
  • Pharmacogenetics
  • Time course transcriptomic analysis of adipogenic differentiation of human white adipose tissue (WAT)-derived stromal cells
  • Determinants of Dental Pulp Stem Cell Heterogeneity
  • Effects of tetramethylpiperidine (TMP)-substituted phenazines on membrane stability and P-glycoprotein function
  • Consequences of HIV infection in the bone marrow niche
  • Heterogeneity of cell therapy products
  • Induction of neutrophil extracellular traps (NETs) by the pneumococcal toxin, pneumolysin (Ply)
  • HIV and haematopoiesis
  • S47 Pneumolysin promotes neutrophil: platelet aggregation in vitro
  • Effect of 2-methoxyestradiol treatment on early- and late-stage breast cancer progression in a mouse model
  • Who is responsible for protecting my health during the COVID- 19 pandemic?
  • The c-Myc/TBX3 Axis Promotes Cellular Transformation of Sarcoma-Initiating Cells
  • Exploiting deterministic maintenance opportunity windows created by conservative engineering design rules that result in free time locked into large high-speed coupled production lines with finite buffers
  • The role of reactive oxygen species in adipogenic differentiation
  • Does in utero HIV exposure and the early nutritional environment influence infant development and immune outcomes? Findings from a pilot study in Pretoria, South Africa
  • Does in utero HIV-exposure and the early nutritional environment influence infant development and immune outcomes? Findings from a pilot study in Pretoria, South Africa
  • Side Population: Its Use in the Study of Cellular Heterogeneity and as a Potential Enrichment Tool for Rare Cell Populations
  • The Role of Pref-1 during Adipogenic Differentiation: An Overview of Suggested Mechanisms
  • Single-Cell Transcriptome Analysis of Human Adipose-Derived Stromal Cells Identifies a Contractile Cell Subpopulation
  • An In Vitro and In Vivo Comparison of Osteogenic Differentiation of Human Mesenchymal Stromal/Stem Cells

Chrisna Durandt's public data